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Christian mang Ang II Mang CF Mang CF Erbelding Mang CF Geber Mang CF Kilbinger nitric oxide Johannes Gutenberg Universität Mainz Clinical Pharmacology Naunyn Schmiedeberg cholinergic neurotransmission acetylcholine release increased basal receptor antagonists human detrusor inhibitory effects guinea-pig ileum myenteric plexus-longitudinal muscle muscle contraction endothelial cells mg kg day smooth muscle oxidative stress pentaerythritol tetranitrate reactive oxygen species angiotensin II eNOS uncoupling apoE-KO mice electrical field stimulation human endothelial non-selective NSAIDs knockout mice eNOS expression mg irbesartan antagonistic effects mg valsartan irbesartan valsartan schild regression candesartan cilexetil antagonistic activity Belz GG Butzer Belz GG Mutschler concentration-response curves isolated human valsartan losartan angiotensin II antagonistic pharmacological potency radioreceptor assay electrically evoked
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